A number of High School and Youth Footbal teams run the Single Wing out of a Balanced Line Formation. A handfull of youth football leagues even require a balanced line. Menominee High School in Michigan has run balanced line Single Wing for over 25 years, many successfull youth teams do the same.
The GOD blocking rules don’t change a bit, but you would pull your LG on 16 powers, and 18 sweeps instead of the RG. It is very doable and the changes are minimal.